The RAC Alpha Serine/Threonine Protein Kinase pipeline drugs market research report outlays comprehensive information on the RAC Alpha Serine/Threonine Protein Kinase targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the RAC Alpha Serine/Threonine Protein Kinase pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Hematological Disorders, Non Malignant Disorders, and Undisclosed which include the indications Solid Tumor, Endometrial Cancer, Sickle Cell Disease, Proteus Syndrome, and Unspecified Rare Disease. It also reviews key players involved in RAC Alpha Serine/Threonine Protein Kinase targeted therapeutics development with respective active and dormant or discontinued products.
The RAC Alpha Serine/Threonine Protein Kinase pipeline targets constitutes close to 15 molecules. Out of which, approximately 11 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 1, 1, 3, 3, 2, and 1 respectively. Similarly, the universities portfolio in Phase I, Preclinical, and Discovery comprises 1, 2, and 1 molecule.
RAC Alpha Serine/Threonine Protein Kinase overview
RAC-alpha serine/threonine-protein kinase is an enzyme encoded by the AKT1 gene. It regulates many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine or threonine phosphorylation of a range of downstream substrates. It regulates the storage of glucose in the form of glycogen by phosphorylating GSK3A and GSK3B resulting in inhibition of its kinase activity. It act as key modulator of the AKT-mTOR signaling pathway controlling the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I).
For a complete picture of RAC Alpha Serine/Threonine Protein Kinase’s drug pipeline, buy the report here.
Data Insights
From
The gold standard of business intelligence.
Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.