The Serine Peptidase Inhibitor Kazal Type pipeline drugs market research report outlays comprehensive information on the Serine Peptidase Inhibitor Kazal Type targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Serine Peptidase Inhibitor Kazal Type pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Genetic Disorders, and Dermatology which include the indications Netherton Syndrome (Trichorrhexis Invaginata, Bamboo Hair), Dermatology, and Atopic Dermatitis (Atopic Eczema). It also reviews key players involved in Serine Peptidase Inhibitor Kazal Type targeted therapeutics development with respective active and dormant or discontinued products.
The Serine Peptidase Inhibitor Kazal Type pipeline targets constitutes close to five molecules. Out of which, approximately five molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase I, and Preclinical stages are 1, 1, and 2 respectively.
Serine Peptidase Inhibitor Kazal Type overview
Serine Peptidase Inhibitor, Kazal Type (SPINK) is a family of proteins known for their role as inhibitors of serine proteases. The Kazal-type inhibitors, characterized by a specific protein domain known as the Kazal domain, act to regulate the activity of serine proteases by binding to them and inhibiting their enzymatic function. The Kazal domain is a conserved structural motif that forms a stable complex with the active site of serine proteases, effectively blocking their catalytic activity. SPINK proteins, through their Kazal-type inhibition, contribute to the fine-tuning of proteolytic processes, preventing excessive or inappropriate protease activity in different tissues and biological contexts. SPINK proteins have been implicated in various physiological and pathological conditions, including inflammation, cancer, and skin disorders. Their dysregulation can lead to imbalances in protease activity, potentially contributing to disease progression.
For a complete picture of Serine Peptidase Inhibitor Kazal Type’s drug pipeline, buy the report here.
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