STP-938 is under clinical development by Step Pharma and currently in Phase II for Follicular Lymphoma. According to GlobalData, Phase II drugs for Follicular Lymphoma have a 46% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how STP-938’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
STP-938 is under development for the treatment of autoimmune disorder such as rheumatoid arthritis, inflammation, solid tumors and hematological malignancies such as b-cell lymphoma including mantle cell lymphoma, diffuse large b-cell lymphoma, peripheral t-cell lymphomas, marginal zone b-cell lymphoma, follicular lymphoma and cutaneous t-cell lymphoma and mantle cell lymphoma. The drug candidate is administered through the oral route. The drug candidate acts by targeting CTP synthase 1 (cytidine triphosphate synthase).
Step Pharma overview
Step Pharma is a pharmaceutical company that discovers and develops novel therapeutics. The company develops a new class of oral nucleotide synthesis inhibitors against cytidine triphosphate synthase 1 (CTPS1) inhibitors. Its candidate is STP938, a small molecule inhibitor of CTPS1 currently in non-clinical development. Step Pharma’s product is used in the treatment of an array of auto-immune and oncology diseases, and blood cancers. The company collaborates with academic laboratories, clinical centers, and biopharmaceutical industry leaders to commercialize its programs and products. Its investors include Pontifax, Sygnature Discovery, Kurma Partners, and Idinvest Partners, among others. Step Pharma is headquartered in Archamps, Auvergne, France.
For a complete picture of STP-938’s drug-specific PTSR and LoA scores, buy the report here.