The Systolic Heart Failure drugs in development market research report provides comprehensive information on the therapeutics under development for Systolic Heart Failure, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses key aspects of the companies and drugs in development for Systolic Heart Failure. Buy the report here.

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The report also covers the descriptive pharmacological action of the therapeutics and the latest news and press releases. Additionally, the report provides an overview of the key players involved in therapeutic development for Systolic Heart Failure and features dormant and discontinued products.

GlobalData tracks 28 drugs in development for Systolic Heart Failure by 26 companies/universities/institutes. The top development phase for Systolic Heart Failure is phase ii with 12 drugs in that stage. The Systolic Heart Failure pipeline has 28 drugs in development by companies and 0 by universities/ institutes. Some of the companies in the Systolic Heart Failure pipeline products market are: BioCardia, Novo Nordisk and Bristol-Myers Squibb.

The key targets in the Systolic Heart Failure pipeline products market include Sodium/Glucose Cotransporter 2 (Low Affinity Sodium-Glucose Cotransporter or Solute Carrier Family 5 Member 2 or SGLT2 or SLC5A2), Type 1 Angiotensin II Receptor (AT1AR or AT1BR or Angiotensin II Type 1 Receptor or AGTR1), and Receptor Tyrosine Protein Kinase ERBB 4 (Tyrosine Kinase Type Cell Surface Receptor HER4 or Proto Oncogene Like Protein c ErbB 4 or p180erbB4 or HER4 or ERBB4 or EC 2.7.10.1).

The key mechanisms of action in the Systolic Heart Failure pipeline product include Sodium/Glucose Cotransporter 2 (Low Affinity Sodium-Glucose Cotransporter or Solute Carrier Family 5 Member 2 or SGLT2 or SLC5A2) Inhibitor with four drugs in Pre-Registration. The Systolic Heart Failure pipeline products include seven routes of administration with the top ROA being Oral and seven key molecule types in the Systolic Heart Failure pipeline products market including Small Molecule, and Cell Therapy.

Systolic Heart Failure overview

Systolic heart failure is a cardiovascular disorder marked by specific features, including the enlargement of the heart’s ventricles, resulting in reduced ejection fraction, a measure of the heart’s pumping efficiency. This condition can manifest as either a chronic, long-term issue or an acute, sudden onset event. However, in both forms, a critical factor contributing to the progression of systolic heart failure is left ventricular remodeling. This process involves structural and functional changes in the left ventricle of the heart, ultimately impacting its ability to pump blood effectively. These alterations in heart shape and function lead to a vicious cycle of deteriorating cardiac performance, making left ventricular remodeling a central concern in the management and understanding of systolic heart failure.

For a complete picture of Systolic Heart Failure’s pipeline drug market, buy the report here.

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GlobalData’s pipeline drugs offers detailed profiles of pharmaceutical drugs in all stages of pre-clinical and clinical development, from discovery through to pre-registration. Coverage is limited to novel human medicinal drugs and biosimilars seeking market approval proprietary and is one of two primary repositories of pharmaceutical drug information offered by GlobalData through its Pharmaceutical Intelligence Center.