The Transthyretin pipeline drugs market research report outlays comprehensive information on the Transthyretin targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Transthyretin pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Metabolic Disorders, Ophthalmology, Gastrointestinal, and Infectious Disease which include the indications Familial Amyloid Cardiomyopathy, Amyloid Cardiomyopathy, Juvenile Macular Degeneration (Stargardt Disease), Unspecified Ophthalmological Disorders, Ulcerative Colitis, Crohn’s Disease (Regional Enteritis), and Coronavirus Disease 2019 (COVID-19) Associated Acute Respiratory Distress Syndrome. It also reviews key players involved in Transthyretin targeted therapeutics development with respective active and dormant or discontinued products.
The Transthyretin pipeline targets constitutes close to 22 molecules. Out of which, approximately 21 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Filing rejected/ Withdrawn, Phase III, Phase II, Phase I, Phase 0, Preclinical, and Discovery stages are 2, 1, 3, 4, 3, 1, 3, and 4 respectively. Similarly, the universities portfolio in Phase III comprises 1 molecule.
Transthyretin overview
Transthyretin is a transport protein. It transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome.
For a complete picture of Transthyretin’s drug pipeline, buy the report here.
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