Tulmimetostat is under clinical development by MorphoSys and currently in Phase I for Mycosis Fungoides. According to GlobalData, Phase I drugs for Mycosis Fungoides have an 85% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Tulmimetostat’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Tulmimetostat overview

Tulmimetostat is under development for the treatment of the solid tumors including metastatic castration-resistant prostate cancer, mycosis fungoides, Sezary syndrome, peripheral T-cell lymphoma (PTCL), relapsed urothelial carcinoma, relapsed ovarian clear cell carcinoma, fallopian tube cancer, peritoneal cancer, relapsed endometrial carcinoma, malignant mesothelioma and relapsed or refractory lymphomas of T-cell. It is administered through oral route and is a new molecular entity. The drug candidate is a second generation EZH2 molecule. It acts by targeting histone lysine N methyltransferase EZH1 and EZH2. It was under development for the treatment of bladder cancer.

MorphoSys overview

MorphoSys is a commercial-stage biopharmaceutical company that develops monoclonal antibodies for therapeutic and research applications, with a focus on the treatment of cancer and autoimmune diseases. The company’s product pipeline includes tafasitamab, pelabresib, cpi-0209, gantenerumab, otilimab, ianalumab, abelacimab, felzartamab, setrusumab, NOV-8, NOV-14 and MOR210. Its Tafasitamab is a humanized Fc-modified cytolytic CD19 targeting monoclonal antibody directed against CD19 in clinical development for the treatment of B cell malignancies. The company provides clinical trials for cancer and inflammatory disorders. MorphoSys also conducts research and development activities with pharmaceutical and biotechnology companies. The company owns a regional licensing agreement to develop and commercialize products. It operates in the US. MorphoSys is headquartered in Planegg, Bayern, Germany.

For a complete picture of Tulmimetostat’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 7 February 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.