United Therapeutics has been granted a patent for a method to treat pulmonary arterial hypertension (PAH) by administering endothelial progenitor cells treated with prostacyclin. Another claim involves treating pulmonary hypertension with mesenchymal stem cells contacted with prostacyclin. GlobalData’s report on United Therapeutics gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on United Therapeutics, Cancer treatment biomarkers was a key innovation area identified from patents. United Therapeutics's grant share as of January 2024 was 46%. Grant share is based on the ratio of number of grants to total number of patents.
A recently granted patent (Publication Number: US11839631B2) discloses a method for treating pulmonary hypertension by administering a combination of a first prostacyclin and mesenchymal stem cells (MSCs) to a subject suffering from the condition. The MSCs are pre-treated with a second prostacyclin before administration, with the option of using the same prostacyclin for both treatments. The first prostacyclin can be treprostinil, and it can be co-administered with MSCs or administered before or after MSCs.
Furthermore, the method allows for the ex vivo contact of MSCs with the second prostacyclin, along with the option of adding a growth factor during this process. The MSCs can be obtained from the subject themselves, offering a personalized approach to treatment. This method is particularly beneficial for patients suffering from pulmonary arterial hypertension, providing a novel and potentially effective therapeutic strategy for managing this condition.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
