Vertex Pharmaceuticals. has filed a patent for a cell housing device with an array of chemicals to increase surface area to volume ratio. The method involves sintering and fusing membranes to create compartments for cell populations. GlobalData’s report on Vertex Pharmaceuticals gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Vertex Pharmaceuticals, Human telomerase RT biomarker was a key innovation area identified from patents. Vertex Pharmaceuticals's grant share as of January 2024 was 44%. Grant share is based on the ratio of number of grants to total number of patents.

Cell housing device with array of chemicals to increase surface area

Source: United States Patent and Trademark Office (USPTO). Credit: Vertex Pharmaceuticals Inc

A patent application (Publication Number: US20240033216A1) describes a method for manufacturing a cell housing device. The process involves sintering a first membrane and/or a second membrane before fusing them together to create a compartment for housing a population of cells. Additional steps include forming channels between the membranes, heating the first membrane to create channels, and using a mold for fusion. The method also involves striking the first membrane with a fusion tool, embossing the membrane, laser ablating portions within the channels, and coating the device with a hydrophilic polymer.

Furthermore, the method specifies parameters such as temperature, pressure, and time for various stages of the manufacturing process. The membranes used in the device can be made of materials like PVDF, PTFE, ePTFE, PCL, and others, with specific characteristics such as pore size and surface area to volume ratio. The resulting compartment can be filled with a cell population capable of glucose-stimulated insulin secretion (GSIS), and at least one of the membranes is semi-permeable. Overall, the method outlined in the patent application provides a detailed and systematic approach to manufacturing a cell housing device with specific features and functionalities for various applications in the field of cell biology and biotechnology.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies