VG-201 is under clinical development by Virogin Biotech and currently in Phase I for Pancreatic Cancer. According to GlobalData, Phase I drugs for Pancreatic Cancer have a 74% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how VG-201’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

VG-201 overview

VG-201 is under development for the treatment of CEA high solid tumors including duodenal cancer, pancreatic cancer, ovarian cancer, leiomyosarcoma, salivary gland cancer, hepatocellular carcinoma, bile duct cancer (cholangiocarcinoma), colorectal cancer, colon cancer, non-small cell lung cancer, neuroendocrine cancer. It is administered by intratumor route. The therapeutic candidate is an oncolytic virus with payloads IL12 and IL15/IL15Ralpha. It is developed based on Transcription and Translation Dual Regulated (TTDR) oncolytic virus platform.

Virogin Biotech overview

Virogin Biotech is a pharmaceutical company. It develops immunotherapies and oncolytic virotherapies that improve systemic antitumor immunity using oncolytic HSV-1 platform and Prime-Boost Approach. The company’s pipeline products include VG161, VG201, VG203, VG301, VGXXX. Its pipeline candidates treat Attenuated (ICP 34.5 deletion), and tumors. The company works in collaboration with research institutes, biotechnology, and pharmaceutical companies. It operates research and development hubs in Vancouver, Canada; and Shanghai, China. Virogin Biotech is headquartered in Vancouver, British Colombia, Canada.

For a complete picture of VG-201’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 22 January 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.