VIP-236 is under clinical development by Vincerx Pharma and currently in Phase I for Solid Tumor. According to GlobalData, Phase I drugs for Solid Tumor have a 60% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how VIP-236’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
VIP-236 is under development for the treatment of advanced and metastatic solid tumors like small cell lung cancer (SCLC), non-small cell lung cancer, renal cell carcinoma(RCC), ovarian cancer, colorectal cancer (CRC), triple negative breast cancer(TNBC) and ovarian cancer, breast cancer, sarcomas, endometrial cancer, gastric cancer. It is administered by intravenous route. The drug candidate is a small molecule drug conjugate (SMDC) consisting of an alpha v beta 3 integrin binder and a linker that is cleavable by neutrophil elastase. The payload is a modified camptothecin derivative designed for extracellular release.
Vincerx Pharma overview
Vincera Pharma Inc (Vincera) is a clinical-stage biopharmaceutical company. It discovers and develops therapies for the treatment of cancer. The company’s pipeline product candidates include enitociclib, a CDK9 Inhibitor for MYC-rearranged DLBCL, and Non-GCB DLBCL and Peripheral T-cell Lymphoma. Vincera other pipeline includes VIP236 for the treatment of multiple solid tumors; VIP943, a KSP inhibitor against leukemia, VIP924, an antibody-drug conjugate to treat B-cell malignancies. The company is evaluating therapeutic programs for solid and hematologic tumors. It also utilizes its proprietary bio conjugate platform to develop therapies in the areas of oncology. Vincera is headquartered in Santa Clara, California, the US.
For a complete picture of VIP-236’s drug-specific PTSR and LoA scores, buy the report here.