ZEN-3694 is under clinical development by Zenith Epigenetics and currently in Phase I for Solid Tumor. According to GlobalData, Phase I drugs for Solid Tumor have a 54% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ZEN-3694’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

ZEN-3694 overview

ZEN-3694 is under development for the treatment of metastatic castration-resistant prostate cancer, acute myelocytic leukemia, solid tumors such as epithelial ovarian cancer, lung cancer, colon cancer, lymphoma, pancreatic cancer, melanoma, NUT midline carcinoma, triple negative breast cancer, ovarian cancer, fallopian tube cancer and primary peritoneal carcinoma. The drug candidate is administered through oral route. The drug candidate acts by targeting BRD2, BRD3, BRD4 and BRDT.

Zenith Epigenetics overview

Zenith Epigenetics, a subsidiary of Zenith Capital Corp, is a clinical-stage biotechnology company that focuses on the discovery and development of small molecules for the inhibition of BET bromodomains. The company’s lead product ZEN-3694 is a BET inhibitor intended for the treatment of solid tumors, including metastatic prostate cancer. Its platform integrates structural biology, medicinal chemistry and modeling with biochemical and cell-based assays. The company has a presence in Canada and the US. Zenith Epigenetics is headquartered in Calgary, Alberta, Canada.

For a complete picture of ZEN-3694’s drug-specific PTSR and LoA scores, buy the report here.

GlobalData

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.