Zetomipzomib maleate is under clinical development by Kezar Life Sciences and currently in Phase II for Autoimmune Hepatitis. According to GlobalData, Phase II drugs for Autoimmune Hepatitis does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Zetomipzomib maleate LoA Report. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Zetomipzomib maleate overview

Zetomipzomib maleate is under development for the treatment of systemic lupus erythematosus with or without lupus nephritis, autoimmune hepatitis and idiopathic inflammatory myopathy including dermatomyositis and polymyositis. It is administered by subcutaneous and intravenous route of administration. The drug candidate is an analog of ONX 0914 and acts by targeting immunoproteasome LMP7. It was also under development for acquired (autoimmune) hemolytic anemia, immune thrombocytopenic purpura. It is being developed based on Protein Secretion Inhibition platform.

Kezar Life Sciences overview

Kezar Life Sciences is a clinical-stage biotechnology company. It discovers and develops small molecule therapies to treat autoimmunity and cancer. The company offers products such as KZR-616 and KZR-261. It is involved in the treatment of various autoimmune diseases, lupus nephritis, solid tumors, oncology, immunology and idiopathic inflammatory myopathies. Kezar Life Sciences’ product KZR-616 is a selective immunoproteasome inhibitor used for the treatment of chronic immune-mediated diseases. The company also discovers and develops targeted cancer and immuno-oncology indications using its protein secretion pathway research platform. Kezar Life Sciences is headquartered in South San Francisco, California, the US.

For a complete picture of Zetomipzomib maleate’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 2 September 2023

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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.