Japanese company Astellas Pharma has concluded the acquisition of 100% equity in US-based biotechnology firm Mitobridge for a total of $225m, making the firm its wholly owned subsidiary.

Mitobridge shareholders will potentially receive additional payments of up to $225m from Astellas based on the progress of clinical development programmes.

The deal bolsters Astellas’ research and development (R&D) in diseases caused due to mitochondrial dysfunctions and will allow the firm to provide new treatment options.

Astellas originally exercised its exclusive option to buy Mitobridge in November last year under the amended terms of their 2013 partnership agreements, which covered R&D collaboration to discover and develop drugs targeting mitochondrial function.

At the time of the announcement, Astellas Pharma president and CEO Yoshihiko Hatanaka said: “Astellas has increased the involvement in mitochondrial drug discovery through its partnership with Mitobridge and the network of key scientists that the company has assembled.

“Through the acquisition of Mitobridge, Astellas accelerates our investment in diseases caused by mitochondria dysfunctions in order to deliver innovative new treatment options to patients.”

“Through the acquisition of Mitobridge, Astellas accelerates our investment in diseases caused by mitochondria dysfunctions in order to deliver innovative new treatment options to patients.”

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

The firm has recently obtained orphan drug designation from the European Commission (EC) for the use of its investigational candidate, gilteritinib, to treat acute myeloid leukaemia.

Gilteritinib is reported to have demonstrated inhibitory activity against two common FLT3 mutations found in around one-third of AML patients.

The drug candidate is being studied in multiple Phase III clinical trials in different populations of FLT3 mutation-positive subjects suffering from AML.