Micrograph of a low malignant potential mucinous ovarian tumour. Credit: Nephron/ commons.wikimedia.org.

Australian biotechnology company Cartherics has granted licence for CTH-004, its autologous CAR-T cell product, to Chinese company Shunxi.

Under the deal terms, Shunxi will have licence to develop, manufacture, and commercialise CTH-004 to treat several solid tumours including ovarian cancer in Greater China, including Hong Kong, Taiwan, Mainland China, and Macao.

Related Company Profiles

View all

Cartherics will retain all the development and commercialisation rights for the therapy outside Greater China.

Shunxi will also hold an option to negotiate rights to other CAR-T products, which include the licenced IP.

CTH-004 is developed by genetically altering patient T cells for inserting a chimeric antigen receptor (CAR) to target a marker (TAG-72) on ovarian cancer cells and delete genes which are involved in T cell function suppression.

See Also:

In animal models of ovarian cancer, it demonstrated promising results.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

The therapy is planned to be assessed in a clinical trial under a research and development partnership with the Peter MacCallum Cancer Centre, which was announced earlier this year.

Cartherics CEO Alan Trounson AO said: “We are pleased to see this potentially effective therapy for ovarian cancer being adopted and trialled in China where there are many women suffering the heavy burden of ovarian cancer.

“We hope that women worldwide will benefit from this therapy.”

The company stated that the agreement structure includes a licence fee, milestone payments, as well as royalties.

Additionally, both the companies will share CTH-004 pre-clinical and clinical data in future.

According to Cartherics, nearly 207,000 deaths and 314,000 new ovarian cancer cases were reported in 2020 across the world.

Editorial content is independently produced and follows the highest standards of journalistic integrity. Topic sponsors are not involved in the creation of editorial content.