Cholesgen (Shanghai) has announced a three-year partnership with AstraZeneca to advance research and development (R&D) in hypercholesterolemia and related metabolic diseases.

The companies will validate genetic drug targets and advance therapeutic molecules into clinical development. 

By leveraging their complementary strengths, they will focus on selected targets from the early stage portfolios of Cholesgen.

AstraZeneca BioPharmaceuticals R&D executive vice-president Mene Pangalos stated: “This is an important collaboration for AstraZeneca, led by deep scientific expertise and a shared ambition to address the key drivers that contribute to hypercholesterolemia and related metabolic diseases.

“We look forward to working together to accelerate target discovery and preclinical research in this area of high unmet need.”

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData

Cholesgen will be eligible for an initial payment and a pre-defined licence package for each drug candidate qualified and nominated by AstraZeneca to advance into clinical development.

Scientists from both Cholesgen and AstraZeneca will work together to validate targets and generate promising results for potential drug candidates, under a joint research committee governance.

AstraZeneca will have a priority option to advance these into clinical development.

SAB Cholesgen chair Dr Bao-Liang Song stated: “As a young biotech with a deep understanding of target biology and a focused pipeline, Cholesgen is thrilled to start this strategic collaboration with AstraZeneca and hopes to accelerate the delivery of innovative medicines for patients with hypercholesterolemia or related metabolic diseases.”

Cholesgen is also engaged in target identification, as well as first-in-class drug discovery in the field of cholesterol-related diseases, including obesity, atherosclerosis, nonalcoholic steatohepatitis and hyperlipidemia.

Early R&D projects coverage on Pharmaceutical Technology is supported by Mimotopes.

Editorial content is independently produced and follows the highest standards of journalistic integrity. Topic sponsors are not involved in the creation of editorial content.