Daiichi Sankyo has obtained marketing approval in Japan for its minnebro and tarlige tablets to treat hypertension and peripheral neuropathic pain (PNP) respectively.

Minnebro was identified during a partnership with US-based drug discovery company Exelixis and was then developed by Daiichi Sankyo.

The approval is based on data from Phase III clinical studies, including ESAX-HTN trial that compared the safety and efficacy of the drug with eplerenone in Japanese essential hypertension patients.

Minnebro is being further evaluated by Daiichi Sankyo in a separate Phase III trial involving patients suffering from diabetic nephropathy in Japan.

“We are committed to using resulting collaboration revenues to reinvest in our business, build our pipeline, and pursue long-term, sustainable growth.”

The collaboration will see with Daiichi Sankyo pay Exelixis $20m in milestone payment upon the first commercial sale of the drug in Japan.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Exelixis president and CEO Michael Morrissey said: “The approval of minnebro brings an important new therapeutic option to clinicians in Japan.

“As partnered compounds like Minnebro are commercialised, we are committed to using resulting collaboration revenues to reinvest in our business, build our pipeline, and pursue long-term, sustainable growth.”

The approval granted for tarlige comes after a review of data from a Phase III trial in diabetic peripheral neuropathic pain (DPNP) patients and another study in subjects with postherpetic neuralgia (PHN).

Tarlige is an Alpha2delta ligand that binds to the respective subunits of voltage-dependent calcium channels.

Daiichi Sankyo and UCB Japan have received approval for the expanded indication of vimpat tablets. This adds a new dosage and administration regimen for paediatric epilepsy patients with partial onset seizures with or without secondary generalisation.