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February 5, 2020updated 13 Feb 2020 10:44am

Regeneron and HHS expand alliance to develop coronavirus drugs

Regeneron Pharmaceuticals has expanded its ongoing partnership with the US Department of Health and Human Services (HHS) for the development of treatments to combat the new coronavirus, 2019-nCoV.


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Regeneron Pharmaceuticals has expanded its ongoing partnership with the US Department of Health and Human Services (HHS) for the development of treatments to combat the new coronavirus, 2019-nCoV.

The company will work with the Biomedical Advanced Research and Development Authority (BARDA) at HHS’ Office of the Assistant Secretary for Preparedness and Response (ASPR) to create several monoclonal antibodies targeting the virus.

Regeneron’s monoclonal antibody discovery platform, VelocImmune, will be leveraged to develop the monoclonal antibodies, which attach to a virus’ proteins and reduce its ability to infect human cells.

VelocImmune is part of the company’s VelociSuite technology, previously leveraged to develop a three-antibody therapeutic to fight the ongoing Ebola outbreak in the Democratic Republic of the Congo.

Furthermore, the technology was used for a two-antibody therapeutic to treat Middle East Respiratory Syndrome coronavirus (MERS-CoV), cutting the development time from years to months.

VelociSuite reduced the time taken for antibody discovery and selection, preclinical-scale manufacturing and clinical-scale manufacturing, among other drug development stages.

Regeneron Pharmaceuticals president and chief scientific officer George Yancopoulos said: “The life-saving results seen with our investigational Ebola therapy last year underscore the potential impact of Regeneron’s rapid response platform for addressing emerging outbreaks.

“Our unique suite of technologies expedites and improves the drug discovery and development process at every stage, positioning Regeneron to respond quickly and effectively to new pathogens.”

HHS and Regeneron signed an agreement in 2017 to discover, research, develop and manufacture antibodies targeting up to ten pathogens, now including the new coronavirus and influenza virus.

BARDA director Rick Bright said: “Emerging infectious diseases can present serious threats to our nation’s health security. Working as public-private partners as we have with Regeneron since 2014, we can move rapidly to respond to new global health threats.”

Currently, the partners have multiple active partnerships, including Regeneron’s investigational Ebola drug REGN-EB3.

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Navigate your business through the ‘new normal’

COVID-19 continues to dominate headlines the world over. It has already affected our lives forever. The way we work, shop, eat, seek medical advice, and socialize will all be different in the future. Quite how different remains to be seen, but all industries must plan for multiple eventualities.  Faced with an explosion of conflicting information on how to plan and implement successful recovery strategies, decision-makers are in dire need of a single, reliable source of intelligence.   GlobalData’s COVID-19 Executive Briefing gives you access to unparalleled data and insights to successfully navigate the uncertain road to recovery across the world’s largest industries. Understand every aspect of this disruptive theme by delving into: 
  •  COVID-19 infection update, with statistics on the spread, testing by country, as well as the latest data on vaccines and therapeutic developments 
  • Economic impact overview, covering stock market indices, GDP, unemployment rates, policy responses & GlobalData’s economic recovery scorecards 
  • Sector developments, with access to sector insight summaries, cross-sector indices and the leaders and laggards in each industry vertical 
Whatever your company’s imminent strategic plans, the long-lasting impact of COVID-19 must not be overlooked. Find out how to futureproof your business operations – download our report today. 
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