AstraZeneca cholesterol drug Crestor drove the company’s third-quarter financials forward as generic competition significantly affected other medications.

Although revenues fell 2% to approximately $8.2bn, Crestor reported a sales increase of 14% to $1.66bn, with US sales rising 20% and total prescriptions up 3%.

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The company also benefitted from strong performances from the antipsychotic Seroquel and Seroquel XR, with sales rising 4% and 24% respectively.

AstraZeneca’s oncology portfolio fell significantly, however, with a number of patent expiries impacting on drug performance. Arimidex sales fell 44% to $176m, whereas Casodex declined by 9%.

AstraZeneca chief executive David Brennan said: "We have delivered a third-quarter revenue and core earnings performance in line with our expectations, against the backdrop of anticipated generic competition and government price interventions."

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Nominations are now closed for the Pharmaceutical Technology Excellence Awards. A big thanks to all the organisations that entered – your response has been outstanding, showcasing exceptional innovation, leadership, and impact.

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Awarded the 2025 Pharmaceutical Technology Excellence Award for Business Expansion in Integrated Manufacturing, Upperton Pharma Solutions is rapidly expanding its UK GMP and sterile manufacturing footprint. Find out how Upperton’s integrated CDMO model helps pharma companies move from early development to clinical and niche commercial supply with fewer handovers and faster timelines.

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