Novartis has acquired US-based hematologic and inflammatory disorder theraputics developer Selexys Pharmaceuticals in a deal valued at approximately $665m.

The company exercised its acquisition right after receiving results of the Sustain study, a Phase II trial evaluating the use of an anti-P-selectin antibody called SelG1, in the reduction of vaso-occlusive pain crises in patients with sickle-cell disease (SCD).

Novartis oncology CEO Bruno Strigini said: "Sickle-cell disease affects millions of people around the world and there are limited therapies available for treatment of vaso-occlusive pain crises, a very common complication of the disease.

"With this acquisition, Novartis is able to leverage its leadership in haematology research to advance development of a potential new treatment option for patients living with this debilitating condition."

"Novartis obtained the right to acquire Selexys and SelG1 in 2012."

SCD is a hereditary blood disorder characterised by sickle-shaped red blood cells and a lifelong disease with many forms that can range in clinical severity, from asymptomatic to life-threatening.

GlobalData Strategic Intelligence

US Tariffs are shifting - will you react or anticipate?

Don’t let policy changes catch you off guard. Stay proactive with real-time data and expert analysis.

By GlobalData

The major contributors for healthcare encounters in SCD are Vaso-occlusive crises or pain crises that occur episodically when these red blood cells block blood flow through blood vessels.

Selexys Pharmaceuticals president and CEO Dr Scott Rollins said: "Furthermore, the acquisition of Selexys by Novartis represents an important step in the continued development of SelG1, a novel, potential first-in-class therapy for patients with this underserved life-threatening disease."

Novartis obtained the right to acquire Selexys and SelG1 in 2012.


Image: Novartis headquarters in Basel. Photo: courtesy of –Andrew- from Flickr.

Pharmaceutical Technology Excellence Awards - Have you nominated?

Nominations are now open for the prestigious Pharmaceutical Technology Excellence Awards - one of the industry's most recognised programmes celebrating innovation, leadership, and impact. This is your chance to showcase your achievements, highlight industry advancements, and gain global recognition. Don't miss the opportunity to be honoured among the best - submit your nomination today!

Nominate Now