Novartis has received approval from the US Food and Drug Administration (FDA) for its Jadenu (deferasirox) tablets to treat patients with chronic iron overload.
Chronic iron overload is a life-threatening cumulative toxicity, which results from blood transfusions required to treat sickle cell disease, myelodysplastic syndromes, thalassemia and other conditions.
Go deeper with GlobalData
FDA has approved a new oral formulation for Exjade (deferasirox) tablets to treat chronic iron overload due to blood transfusions in patients two years of age and older and chronic iron overload in non-transfusion-dependent thalassemia syndromes (NTDT) in patients ten years of age and older.
Novartis oncology president Bruno Strigini said: "Novartis has had a long-term commitment to improving the lives of patients with chronic iron overload.
"Exjade transformed iron chelation therapy. We responded to feedback from patients and their physicians, and now Jadenu, by simplifying treatment administration, offers an important new option to help meet these patients’ needs."
See Also:
According to the company, the indications are approved under accelerated approval based on a reduction of iron levels in the liver and blood.
How well do you really know your competitors?
Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.
Thank you!
Your download email will arrive shortly
Not ready to buy yet? Download a free sample
We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form
By GlobalDataThe company has also submitted additional regulatory applications for Jadenu in other countries across the globe.
Novartis has established a multi-year collaboration with Aduro Biotech to discover and develop new cancer immunotherapies targeting the stimulator of interferon genes (STING) pathway and launched a new immuno-oncology research group led by cancer vaccine expert Dr Glenn Dranoff.
Under the deal, Aduro will receive an upfront payment of $200m from Novartis. Aduro will secure an initial equity investment of $25m, in addition to another $25m equity investment in the future.
Image: Novartis AG headquarters in Basel. Photo: courtesy of Andrew.
