Bristol Myers Squibb will have exclusive rights to access Tubulis’ platform to develop the ADCs. Credit: Bristol-Myers Squibb Company.

Tubulis has signed a strategic licence agreement with Bristol Myers Squibb for the development of differentiated antibody-drug conjugates (ADCs) to treat cancer patients.

Bristol Myers Squibb will have exclusive rights to access Tubulis’ Tubutecan payloads, combined with its P5 conjugation platform, to develop the ADCs.

Go deeper with GlobalData

Premium Insights

The gold standard of business intelligence.

Find out more

Related Company Profiles

View all

P5 and the Tubutecan payloads can create ultra-stable ADCs that could actively minimise undesirable target-independent toxicities.

The ultra-stable ADCs are also optimised for the delivery of potent topoisomerase-1 inhibitors to their targets.

Bristol Myers Squibb will make an upfront payment of $22.75m to Tubulis.

See Also:

There will also be a possibility of more than $1bn in development, regulatory and commercial milestone payments, along with royalty payments on the subsequently marketed products.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

After Bristol Myers Squibb selects an antibody target, Tubulis will help the firm with its linker payload to create an exclusively matched ADC for each antibody.

Bristol Myers Squibb will be solely responsible for the development, production and commercialisation of the resulting ADCs.

Bristol Myers Squibb research and early development senior vice-president and mechanisms of cancer resistance thematic research centre head Emma Lees stated: “ADCs play a promising role in cancer therapy, and Tubulis’ differentiated technologies offer opportunities to overcome current challenges in the development of safe and effective ADC therapeutics.

“With the P5 platform, we will be able to pair the right antibody with the right payload and thus provide potential for meaningful therapeutic benefits for patients with solid tumours.”

In March 2023, Bristol Myers Squibb also renewed its strategic alliance with Evotec to develop new medicines.