Roquette Pharma Products PEARLITOL® Flash: Orodispersible Solution 20 May 2014 Full company details Follow PEARLITOL® Flash is a mannitol compound that allies robustness with rapid disintegration. It offers the consumer a uniquely pleasing taste experience and makes tablet formulation surprisingly simple. PDF Available Download PEARLITOL® Flash is a compound of mannitol and starch, specially designed to disintegrate rapidly, providing a smooth texture without the addition of a superdisintegrant. In the present study, PEARLITOL® Flash's disintegration properties and mechanism were evaluated. ,PEARLITOL® Flash has been developed as a self-disintegrating mannitol compound for the formulation of ODTs by direct compression. Thanks to its special composition, a very low level of lubricant is necessary. ,See how PEARLITOL Flash allows the production of robust orodispersible tablets even at high-dilution. ,The aim of the study is to determine if commercially available oral disintegrating tablet platforms induce active pharmaceutical ingredient degradation.,Compression forces and tablet hardness versus disintegration rate are key formulation factors. It’s just a question of identifying the ODT excipient that would meet your requirements.