Sama and colleagues conducted a recent study, published in the European Heart Journal, which concluded that men have higher concentrations of angiotensin-converting enzyme (ACE) 2 in their blood in comparison to women and that ACE2 concentrations in heart failure patients are not affected by typically used ACE inhibitors, anti-hypertensives, and angiotensin receptor blockers (ARBs).

Findings from the study led to assumptions that higher levels of ACE2 in men could explain why they appear more vulnerable to Covid-19 than women, as the SARS-CoV-2 virus has been proven to bind to the ACE2 receptor when infecting cells. Read more here.