27 October 2020
The National Institutes of Health (NIH) has announced the closure of enrolment into the LY-CoV555 sub-study being conducted as part of the ACTIV-3 clinical trial. THis is because of a recommendation by the trial’s independent Data and Safety Monitoring Board and a review of the data that indicated low efficacy of monoclonal antibody drug LY-CoV555 in treating hospitalised Covid-19 patients. Developed by Eli Lilly in partnership with AbCellera, LY-CoV555 is one of several investigational agents being evaluated as part of the trial.
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AstraZeneca has reported its Covid-19 vaccine, which is being developed in partnership with the University of Oxford, has generated a similar immunogenicity response in older and younger adults. The vaccine also generated lower adverse reactions in older adults reported CNBC.
GeoVax has signed a license agreement with the NIH for access to the National Institute of Allergy and Infectious Diseases’ (NIAID) patent rights to stabilised Covid-19 spike protein. The company will use the protein in combination with its proprietary technology to develop a vaccine that boosts the immune system against Covid-19.
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Premier and Baxter Healthcare have announced a partnership to provide dexmedetomidine hydrochloride to health providers to stabilise the long-term supply of the drug. The drug is used to treat acute cases of Covid-19 patients who require ventilation. Demand for the drug has increased by more than 360% compared to the same period in 2019.
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