US biotech Moderna has published interim efficacy results from its Phase III trial of mRNA-1273, its vaccine candidate for Covid-19.

This data, which was released by the trial’s data safety monitoring board (DSMB), showed that the trial met its primary efficacy endpoint and the vaccine achieved a 94.5% efficacy. This efficacy analysis is based on 95 cases of Covid-19 – five of which were in the mRNA-1273 group – confirmed within two weeks of the second vaccine dose. The secondary endpoint in the trial focused on analysing severe cases, and findings were included in this interim analysis.

Go deeper with GlobalData

Premium Insights

The gold standard of business intelligence.

Find out more

Related Company Profiles

View all

The DSMB did not report any significant safety concerns linked with the vaccine.

Moderna CEO Stéphane Bancel said: “This is a pivotal moment in the development of our Covid-19 vaccine candidate. Since early January, we have chased this virus with the intent to protect as many people around the world as possible. All along, we have known that each day matters.

“This positive interim analysis from our Phase III study has given us the first clinical validation that our vaccine can prevent Covid-19 disease, including severe disease.

“We look forward to the next milestones of submitting for an EUA [emergency use authorisation] in the US, and regulatory filings in countries around the world, while we continue to collect data on the safety and efficacy of the vaccine in the COVE study.”

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Moderna has been carrying out its Phase III trial of mRNA-1273 in partnership with the US National Institute of Allergy and Infectious Diseases and Biomedical Advanced Research and Development Authority.