Brain

Thomson Reuters‘ Intellectual Property & Science business of has announced it will extend its relationship with One Mind for Research to further the understanding of brain-related injuries.

By collaborating, the companies aim to increase the understanding of the central nervous system (CNS) and traumatic brain injuries (TBI) through tranSMART, an open-source data sharing and analytics platform supported by the tranSMART Foundation.

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Reuters siad that tranSMART will be implemented by the two organisations to support the scientific community’s need to share data, collaborate to improve diagnostics and discover more effective treatments for patients suffering from CNS and TBI-related diseases.

“We are honored to work with One Mind on such a critical project,” said Thomson Reuters Life Sciences vice president Christopher McKenna.

Reuters Life Sciences is made up of a multi-disciplinary team of molecular biologists, bioinformaticians, medicinal chemists and IT engineers.

In the first part of the project, it provided data curation and analysis for preparing and uploading TBI clinical data, performing preliminary data analyses and designing a workflow driven by clinical terminology.

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In the second stage, it will assist One Mind and its partners in using the platform as part of the One Mind Portal, which includes advanced bioinformatics analysis of the molecular data generated in TBI, clinical trials and a customization of tranSMART for an organization’s information portals.

“Web platforms like tranSMART are essential in advancing the work of our community’s researchers, but there are many challenges in constructing and maintaining this type of tool and having it work in unison with the One Mind Portal in development,” added One Mind for Research chief science and technology officer Magali Haas.

Eventually, the two organisations hope to develop the “Apollo Program”: the One Mind Brain Data Exchange Portal.

Using tranSMART, researchers will be able to generate hypotheses on efficacy and toxicity biomarkers, novel drug targets, patient stratification for clinical trials and other clinical applications.

“We are happy to be working with Thomson Reuters on this project. Their expertise and experience have been instrumental in helping craft tranSMART to fit the specific needs of our research community,” added Haas.

Image: The two organisations hope to develop a comrehensive “Apollo Program” where data relating to the brain can be exchanged. Photo: Courtesy of Gaetan Lee.