Lead, Cadmium and Nickel in Magnesium Stearate by ICP-MS
By Butterworth Laboratories
ICP-MS analysis is routinely used to meet ICH Q3D requirements for Elemental Impurities in accordance with the Ph Eur and USP. It was a logical move to show the equivalence of this test to the established Graphite Furnace Atomic Absorption Spectroscopy (GFAAS) outlined in the monographs for Magnesium Stearate. In this whitepaper, Butterworth Laboratories shares its validation of an ICP-MS method to show equivalence to Graphite Furnace Monograph tests for Lead, Cadmium and Nickel.