Pharma Technology Focus | Issue 14 | June 2012

Despite modern software advances, creating an overarching clinical data management strategy is extremely challenging. We speak to clinical data experts about the benefits of adapting data standards and the risks involved if users choose to ignore them.

We also look into the UK Government’s controversial plan to open up clinical patient data to the pharmaceutical industry and cast a critical eye over its opportunities and dangers.

Moreover, we investigate the risks posed by missing or inadequate data, explore the rise of collaborative clinical data software and delve into cloud computing to find out whether this technology can streamline data for the drug industry to make information more accessible.

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In this issue

The Big Picture
Despite modern software advances, creating an overarching clinical data management strategy remains challenging. Octagon Research’s David Evans and Barry Cohen talk to Chris Lo about the benefits of adopting data standards.
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Out of Sight
Unpublished clinical trial data is a persistent problem which stems from the pursuit of safe, evidence-based medicine. Chris Lo investigates the dangers of missing trial data and asks how a more transparent system can be achieved in the future.
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Opening up the NHS
The UK Government’s proposal to open up public healthcare data to pharma companies could boost innovation in the country. Elisabeth Fischer investigates the privacy and organisational concerns that need to be addressed first.
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One for All
As trial data grows in volume and complexity, researchers are finding the load increasingly unmanageable. Elly Earls explores how interoperable software systems could help the sector to stay on top of the data flood.
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Clouds of Change
Excessive data may be to blame for low productivity rates in the drug industry. Sarah Blackman looks at how cloud computing can streamline data and speed up drug discovery.
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Mobile Revolution
Big Pharma is starting to embrace mobile technology, but it still needs to tackle data and structural challenges before it can truly reap the benefits of wireless devices. Elisabeth Fischer reports on recent progress.
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Next Issue: Special Delivery

Nanotechnology has emerged as one of the most exciting new drug delivery technologies. We explore two potential applications in cancer treatment: a chemotherapy drug loaded with nanobubbles, which experts have found to be 30 times more lethal to cancer cells, as well as a star-shaped gold nanoparticle that can deliver drugs directly to the nucleus of a cancer cell.

We also look at other breakthroughs, including an externally controlled wireless device that can be propelled through the blood and a delivery method using 3D superhydrophobic materials, which could control drug absorption over a three-month period, and investigate the science behind new class of highly selective targeted therapeutics known as Accurins, which promise a higher level of accuracy in drug delivery.

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