The Mundipharma network of independent associated companies has purchased worldwide development, commercialisation and production rights to CAP7.1 from CellAct for more than $250m.

CAP7.1 is a new pro-drug of anticancer agent etoposide that is metabolised into an active form by enzymes in the gastrointestinal tract particularly active in tumour cells.

The new therapy has the capability to treat orphan disease designated biliary tract cancer, for which there are no second line treatment options.

CellAct chief executive officer Nalân Utku said: “The proven expertise of Mundipharma in medicines development and their commercial capabilities will enable the potential for CAP7.1 to help patients in this underserved disease area.”

Invented by teaching hospital Charité – Universitätsmedizin Berlin in Germany, CAP7.1 facilitates the focused release of the chemotherapeutic agent into tumour cells in higher doses while ensuring a good safety and tolerability profile.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

See Also:

The CellAct drug will be progressed through Phase III trials to be conducted by EDO, a company with a global network of clinical connections and expertise in developing cancer treatments.

"We are thrilled to be taking this promising treatment into the next phase of clinical trials."

The company will also be responsible for reformulating the treatment to allow manufacturing scale-up.

EDO chief executive officer Dr Thomas Mehrling said: “We are thrilled to be taking this promising treatment into the next phase of clinical trials.

“By working with a network of experienced clinical partners, EDO enables efficient drug development and we believe this will be of benefit to accelerate the development a potentially life-changing treatment in this area of great unmet patient need.”

Under the deal, both CellAct and Charité – Universitätsmedizin Berlin will also receive sales-related income through tiered royalties and milestone payments.

During the Phase II trial of CAP7.1, the drug demonstrated efficacy in the treatment of patients with biliary tract cancer, with 56% of them meeting the primary objective of disease control, including tumour shrinkages.