ABBVCLS-579 is under clinical development by Calico Life Sciences and currently in Phase I for Head And Neck Squamous Cell Carcinoma (HNSC). According to GlobalData, Phase I drugs for Head And Neck Squamous Cell Carcinoma (HNSC) have a 79% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ABBVCLS-579’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
ABBVCLS-579 overview
ABBVCLS-579 is under development for the treatment of advanced or metastatic solid tumors including head and neck cancer squamous cell carcinoma, non-small cell lung cancer, renal cell carcinoma. The drug candidate is administered through oral route as a capsule. It acts by targeting tyrosine-protein phosphatase non-receptor type 1 and 2 (PTPN1 and PTPN2).
Calico Life Sciences overview
Calico Life Sciences (Calico), a subsidiary of Alphabet Inc, is a research and development company. It focuses on the development, discovery, and commercialization of therapies for treating diseases of aging including neurodegeneration and cancer. The company is investing in the investigational eIF2B activator Fosigotifator (ABBV-CLS-7262) for the treatment of vanishing white matter disease. It is also developing ABBV-CLS-579 and ABBV-CLS-484 for the indication of locally advanced or metastatic tumors. Calico partners with organizations like the Broad Institute and AbbVie to advance its drug discovery and development programs. Calico is headquartered in South San Francisco, California, the US.
For a complete picture of ABBVCLS-579’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
