ABBVCLS-579 is under clinical development by Calico Life Sciences and currently in Phase I for Head And Neck Squamous Cell Carcinoma (HNSC). According to GlobalData, Phase I drugs for Head And Neck Squamous Cell Carcinoma (HNSC) have a 79% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ABBVCLS-579’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

ABBVCLS-579 overview

ABBVCLS-579 is under development for the treatment of advanced or metastatic solid tumors including head and neck cancer squamous cell carcinoma, non-small cell lung cancer, renal cell carcinoma. The drug candidate is administered by oral route as a capsule. It acts by targeting tyrosine protein phosphatase non-receptor type 2 (PTPN2).

Calico Life Sciences overview

Calico Life Sciences (Calico) is a research and development company. It is operating its business as Calico Group LLC, is a life extension research and development company. It focusses on the discovery, development, and commercialization of therapies for the treatment of diseases of aging including neurodegeneration and cancer. It is focusing on both basic research and the translation of our discoveries into new interventions that can help people live healthier, and maybe longer, lives. It also engaged in research of advanced technologies to increase understanding of the biology that controls lifespan. Calico is headquartered in South San Francisco, California, the US.

For a complete picture of ABBVCLS-579’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 7 February 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.