Site-Specific Labelling Technology Platform and Products

Flow cytometry detection using fluorescent-labelled proteins that bind specifically to key markers on the cell surface is recognised as the most commonly used detection method. This method is efficient and rapid, enabling the simultaneous detection of multiple targets in a single operation. However, there are several challenges in the selection of fluorescent-labelled proteins. Currently, traditional chemical labelling is the most widely used labelling technology on the market. However, the batch-to-batch consistency is hard to control, making it difficult to provide accurate and stable detection of CAR abundance, affecting efficacy assessment. Therefore, the development of labelled proteins with high activity and batch-to-batch consistency is crucial for cell detection. Sino Biological has successfully developed a wide range of site-specifically labelled proteins that maintain the natural conformation and activity, with high stability and batch-to-batch consistency, enhancing the sensitivity and accuracy of detection. These products have become crucial tools for cell quality control and testing, facilitating the development of cell therapy drugs.