There is very little movement among the top ten Pharma companies from 2015 to 2016. Amgen has now entered the top ten and AstraZeneca has dropped out. Pfizer still holds the number one spot, with its prescription drug revenues pulling further ahead of Novartis, its nearest competitor. Elsewhere in the rankings Sanofi has overtaken Merck in the top five, and Gilead Sciences has dropped to eighth position.