GE Healthcare, Akeso Accelerate Therapy Manufacturing in China

Akeso Pharmaceuticals, a biotech company that focuses in the growth and commercialisation of innovative biologics, will open a facility in Guangzhou, China, based on GE Healthcare Life Sciences’ FlexFactory platform, intended for proficient and cost-effective production of recombinant biologics.

GE Healthcare Life Sciences will speed up Akeso’s access to antibody production in support of Akeso’s pipeline of biopharmaceuticals, including therapies for the treatment of cancer, auto-immune diseases, arthritis, and Crohn’s disease.

Akeso Biopharma chairman and CEO Dr Michelle Xia said: “We strive to provide affordable and high-quality therapeutics to patients. In 2016, we were the first user of FlexFactory for monoclonal antibody-manufacturing in South China.

“Once again, we chose to collaborate with GE to deploy new product lines and boost the production of next-generation immunotherapy drugs in China.”

The FlexFactory will be located on Akeso’s manufacturing site in Guangzhou Knowledge City. It is configured with capacity for 4 x 2000L bioreactors to support the clinical and commercial production of therapeutic antibodies and is cGMP compliant. This becomes the 15th automation-integrated FlexFactory platform provided by GE Healthcare Life Sciences in China, and the 64th FlexFactory supplied globally to manufacturers of biopharmaceuticals.

GE Healthcare Life Sciences general manager of BioPress Olivier Loeillot said: “Akeso is one of China’s most innovative manufacturers of next-generation therapies. Rapid access to proven biomanufacturing technologies, and cost-efficient capabilities – supplied by trusted and seasoned industry partners, are key to realise the potential of the industry. We are supporting the growth of Guangzhou’s biotech with flexible and scalable technologies, like FlexFactory and KUBio, as we recognise the needs of biomanufacturers to succeed in this highly competitive environment.”

China’s biopharmaceutical service sector has been growing at a compound annual growth rate (CAGR) of 30 per cent and is poised to surge to $1.4 billion by 20211. The monoclonal antibody market size in China is projected to reach RMB120.7 billion or $17 billion by 20252.

Akeso Pharmaceuticals is a joint venture between Akeso Biopharma and the Guangzhou Development District. The FlexFactory will support the company’s aim to expand its operations to large-scale manufacturing of biopharmaceuticals, with an initial focus on bispecific antibodies. Akeso’s plant is expected to be operational by end of 2020 and create up to 150 jobs upon opening.

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