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  1. Alconox
4 April 2017

How do you Determine the Optimum Detergency for Liquinox?

Generally, optimum detergency for Liquinox® Critical Cleaning Liquid Detergent is reached at a 1%-2% concentration (optimum defined as amount of soil removed per unit of detergent used).

Maximum detergency is typically reached at a 2%-3% concentration (maximum defined as the total amount of soil removed per area of substrate without regard to amount of detergent used).

The maximum cleaning capacity is often achieved at 4%, or even 6% (cleaning capacity is defined as the amount of total parts cleaned or combined amount of residue removed before you have to change out baths).If you are trying to clean lots of parts before you have to dump your bath, using 2%-3% may make sense. Typically, you have to do extra rinsing to get the highest levels of cleaning when you use more than a 2% concentration of Liquinox.

Other considerations are, whether you are trying to optimise for detergency cleaning capacity, detergent cost, or waste minimisation.

If the answer is "all of these" then 2% is probably a reasonable compromise. Most Alconox, customers are doing very sensitive critical cleaning, so they rarely operate their baths at anywhere near full cleaning capacity. Customers also typically use 1% solutions and dump the bath long before full use of cleaning capacity has been achieved because they are more worried about cross contamination from parts than they are worried about optimising cleaning capacity.

The basic detergency concepts discussed here can be applied across the rest of our detergent portfolio, but the specific concentrations will vary.

Cleaning validation is a requirement for pharmaceutical manufacturing, which adheres to current good manufacturing practice (cGMP) and quality systems regulations (QSR).
The use of aqueous cleaning in pharmaceutical manufacturing can provide numerous benefits in terms of effectiveness, minimal surface residue, and easier cleaning validation.
Cleaning validation is a necessary and time-consuming part of manufacturing pharmaceuticals. The validation process can be expedited and the cost reduced if the cleaner supplier...
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