Malvern Panalytical has announced a series of webinars taking place in May, including ‘The Live Launch of the New Zetasizer Pro and Zetasizer Ultra’, ‘A Basic Introduction to Rheology and Rheometry PART 1 – Viscosity’, ‘Enlightening the Fcab-antigen Interaction via X-ray Crystallography & Solution Studies’, ‘Get the best of both worlds: Coupling advanced multi-detection with UPLC for faster and more detailed polymer analysis’, and ‘Collecting X-ray Powder Diffraction Data: How to Choose the Best Configuration and Measurement Parameters’.

Please make an enquiry if you are interested in registering.

The live launch of the new Zetasizer Pro and Zetasizer Ultra

Since the first commercial dynamic light scattering (DLS) instrument was developed by Malvern Instruments in the early 1970s, Malvern’s name, now strengthened by its evolution into Malvern Panalytical, has been synonymous with expertise and leadership in light scattering technology and particle characterisation.

Today, almost 50 years on, Malvern Panalytical’s technologies are trusted to answer questions, solve challenges, and help deliver high-quality products in many thousands of organisations and industries around the world.

The company is proud of its exceptional heritage, but it is also driven to address the current and future challenges of its customers by pushing the boundaries of science and engineering. Malvern Panalytical continually innovates and tests to develop new technologies and make its established solutions perform even better.

The company focuses not only on how its systems can improve, simplify and accelerate your workflows to improve productivity, but also on how they can rapidly provide more useful data than ever before, giving you absolute confidence in the decisions you need to make.

On May 23rd, 2018, Malvern Panalytical is proud to introduce a major step forward in light scattering characterisation by unveiling the brand-new Zetasizer Pro and Zetasizer Ultra, two flagship systems that deliver the ultimate in particle and molecule size and zeta potential analysis.

Please join the company for the live launch of the Zetasizer Pro and Ultra and let Malvern Panalytical introduce you to the future of light scattering.

This webinar will take place on 9 May from 10:30 (GMT-05:00) to 11:30.

A Basic Introduction to Rheology and Rheometry PART 1 – Viscosity

Rheology is defined as the science of deformation and flow and in particular refers to materials that show viscoelastic or non-Newtonian behaviour when stressed. Such materials include suspensions, emulsions, polymer solutions and foams to name but a few.

The first of this two-part webinar series will focus on viscosity and viscometry, introducing the basic concepts and tests that can performed on a rotational rheometer to measure yield stress, thixotropy, and shear dependent flow properties.

This webinar will take place on 10 May from 10:30 (GMT-05:00) to 11:30.

Enlightening the Fcab-antigen Interaction via X-ray Crystallography & Solution Studies

The modular nature of antibodies allows the design of antibody-related formats with tailored characteristics. The antibody’s Fc part, encompassing the effector functions, represents an attractive scaffold for engineering therapeutic molecules as demonstrated by the generation of Fcabs (Fc domain with antigen-binding sites). By engineering the C-terminal loops (AB, CD and EF loop) in the CH3 domains, two antigen binding sites can be inserted in close proximity.

The study presented in this webinar deals with the determination of the first X-ray structures of three Fcabs that differ in loop design, specificity, affinity and thermal stability and reveals their overall structural integrity and native fold.

Furthermore, by investigation of the interaction of these Fcabs with their respective antigens (HER2 or VEGF) using a set of complementary techniques (X-ray crystallography, size exclusion chromatography combined with multi-angle light scattering [SEC-MALS], isothermal titration calorimetry [ITC], fluorescence correlation spectroscopy [FCS]), insights into the binding modes and binding stoichiometries were gained.

This webinar will take place on 15 May from 10:30 (GMT-05:00) to 11:30.

Get the Best of Both Worlds: Coupling Advanced Multi-Detection with UPLC for Faster and More Detailed Polymer Analysis

Multi-detector gel-permeation chromatography (GPC)/size exclusion chromatography (SEC) offers superior information about polymers, including absolute molecular weight, size, and structure, when compared with conventional single-detector measurements. At the same time, UPLC offers a step-change in the resolution and speed of polymer separations, using small columns and particle sizes to achieve high plate counts.

Previously, these two techniques have been incompatible due to band-broadening and dispersion effects that take place as narrow UPLC peaks pass through multiple detector cells.

The latest enhancements to Malvern Panalytical’s OMNISEC REVEAL detector platform now bring these two class leading technologies together, combining the information-rich data from multi-detector GPC/SEC with the speed and resolution afforded by UPLC (Water’s ACQUITY APC).

Taking place on 17 May from 10:30 (GMT-05:00) to 11:30, this webinar will briefly describe advanced detection and UPLC, and discuss how these two technologies have been brought together. Application examples will be provided showing how this data really can be generated in just a few minutes.

Collecting X-ray Powder Diffraction Data: How to Choose the Best Configuration and Measurement Parameters

X-ray Powder Diffractometers are versatile instruments that often come with a variety of optics and accessories that can be exchanged to optimise measurements. While these options provide flexibility, they can also leave one unsure about the best configuration to use.

This presentation will teach ways to navigate all of the choices and select the best configuration and measurement parameters to collect powder diffraction data from a variety of samples.

This presentation will:

  • Review the common optics used for X-ray powder diffraction and discuss their impact on data quality
  • Discuss how configuration affects aspects such as resolution, intensity and beam size
  • Identify the most critical criteria for collecting accurate data
  • Discuss how different sample types (clinker, mining, chemical, pharmaceutical, advanced materials) place different requirements on measurements
  • Discuss strategies for optimising measurement parameters

This webinar will take place on 22 May from 10:30 (GMT-05:00) to 11:30.

Please make an enquiry if you are interested in registering.