Duke University Health System (DUHS) is a hospital and health care network. Its services consist of primary care, medical and surgical specialities, and subspecialities. DUHS’s health system includes three hospitals – Duke University Hospital, Duke Regional Hospital, and Duke Raleigh Hospital. Duke University Hospital is a research hospital that strives to bring about medical advances and a teaching hospital for students of medicine, nursing, and health sciences. Duke Regional Hospital serves Durham, Orange, Person, Granville, and Alamance counties and focuses on medical care with personalized service. It specializes in bariatric surgery, obstetrics and gynaecology, and vascular disease. Duke Raleigh Hospital offers diagnostic, medical, and surgical services in specialities such as cancer care, cardiology, gastroenterology, lung disease, neurology, neurosurgery, ophthalmology, orthopaedic care, otolaryngology, palliative care, spine and back care, and urology. Duke Health & Well-Being includes a medical-based weight loss program, medical-based fitness, wellness and rehabilitation programs at the Duke Health & Fitness Center and Duke Integrative Medicine.

Duke HomeCare & Hospice offers hospice, home health, and infusion services. It offers hospice care to terminally ill patients in their homes, skilled-nursing facilities, and assisted-living facilities. It provides home health services to homebound patients in need of nursing services, physical therapy, speech therapy, and occupational therapy. It provides infusion services at home or at work for individuals who need intravenous therapy.