Aflibercept biosimilar is under clinical development by Hexal and currently in Phase III for Wet (Neovascular / Exudative) Macular Degeneration. According to GlobalData, Phase III drugs for Wet (Neovascular / Exudative) Macular Degeneration have a 73% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how Aflibercept biosimilar’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Aflibercept biosimilar overview

Aflibercept biosimilar (SOK583A1) is under development for the treatment of wet age-related macular degeneration. It is administered through intravitreal route as solution. The drug candidate acts by targeting placenta growth factor (PGF) and vascular endothelial growth factor A.

Hexal overview

Hexal, formerly HEXAL Gentech Forschungs, a subsidiary of Novartis AG is a healthcare products provider that offers off-patent generic medicines. The company offers patient care, biosimilars and children’s medicines. It offers products in therapeutic areas of allergy, sedative, nervous, cold, fever and pain; skin wounds, baby care, cardiovascular system, blood circulation, muscles, herbal, digestion, vitamins, minerals and dietary supplements and others. The company also offers non-prescription medicines for asthma, hypertension, colds, cancer, osteoporosis, pain, Parkinson’s and other disease treatments. It markets its products across Germany. Hexal is headquartered in Holzkirchen, Germany.

For a complete picture of Aflibercept biosimilar’s drug-specific PTSR and LoA scores, buy the report here.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.