The Aldose Reductase pipeline drugs market research report outlays comprehensive information on the Aldose Reductase targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Aldose Reductase pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Metabolic Disorders, Central Nervous System, Infectious Disease, and Respiratory which include the indications Congenital Disorder of Glycosylation Type I A, Galactosemia, Diabetic Peripheral Neuropathy, Coronavirus Disease 2019 (COVID-19), and Pulmonary Inflammation. It also reviews key players involved in Aldose Reductase targeted therapeutics development with respective active and dormant or discontinued products.
The Aldose Reductase pipeline targets constitutes close to six molecules. Out of which, approximately six molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase I, Preclinical, and Discovery stages are 3, 1, 1, and 1 respectively.
Aldose Reductase overview
Aldose Reductase is an enzyme that in humans is encoded by a gene AKR1B1. This is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. Plays a role in detoxifying dietary and lipid-derived unsaturated carbonyls. This member catalyzes the reduction of several aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.
For a complete picture of Aldose Reductase’s drug pipeline, buy the report here.
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