Alkermes has been granted a patent for a pharmaceutical composition that ensures long-term stability of a hydrolytically labile antipsychotic agent. The composition includes Compound 1. GlobalData’s report on Alkermes gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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Data Insights Alkermes Plc - Company Profile

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According to GlobalData’s company profile on Alkermes, was a key innovation area identified from patents. Alkermes's grant share as of April 2024 was 56%. Grant share is based on the ratio of number of grants to total number of patents.

Long-term stable pharmaceutical composition with hydrolytically labile antipsychotic agent

Source: United States Patent and Trademark Office (USPTO). Credit: Alkermes Plc

The granted patent (Publication Number: US11969469B2) discloses a pharmaceutical composition comprising Compound 1 as a key ingredient. The composition is formulated to contain less than 30 parts per million of the hydrolysis product of Compound 1 after standing for at least 24 months. Additionally, the composition includes a water miscible and/or soluble non-ionic surfactant, specifically a polyoxyethylene derivative of a sorbitan ester of a carboxylic acid with 8-14 carbon atoms, such as sorbitan laurate or polysorbate 20.

Furthermore, the patent claims a pharmaceutical composition with 15-35 weight percent of compound I as a crucial component. The formulation aims to minimize the presence of the hydrolysis product of Compound 1 to ensure stability and efficacy over an extended period. By specifying the type of non-ionic surfactant and the concentration of the active ingredient, the patent provides a clear framework for the development of pharmaceutical compositions with improved shelf-life and performance.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies