Alpha-1 proteinase inhibitor (human) second generation is under clinical development by Kamada Pharmaceuticals and currently in Phase III for Alpha-1 Antitrypsin Deficiency (A1AD). According to GlobalData, Phase III drugs for Alpha-1 Antitrypsin Deficiency (A1AD) does not have sufficient historical data to build an indication benchmark PTSR for Phase III. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Alpha-1 proteinase inhibitor (human) second generation LoA Report. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Alpha-1 proteinase inhibitor (human) second generation overview

Alpha-1 proteinase inhibitor (human) is under development for the treatment of alpha- antitrypsin deficiency (inherited emphysema), cystic fibrosis and bronchiectasis. It is administered through inhalation using e-Flow based inhalation device. The drug candidate is a second generation AAT product. The development of drug candidate is based on e-Flow aerosol technology. It was also under development for cystic fibrosis.

Kamada Pharmaceuticals overview

Kamada Pharmaceuticals (Kamada), is a biopharmaceutical company that develops, manufactures, and commercializes specialty proteins, specific immunoglobulins, and other prescription medicines. Its major products include respiratory, immunoglobins, critical care, and others. It also offers medicines for the treatment of cystic fibrosis, asthma, hemophilia, rabies, hepatitis B and other indications. Kamada’s pipeline products include intravenous and inhaled AAT protein and rabies. Its intravenous formulations are intended for Graft vs Host Disease (GVHD), type-1 diabetes, covid-19, and lung transplantation indications. The company distributes its products through a network of distributors in Brazil, Israel, Russia, India, and other countries in Eastern Europe, Latin America, and Asia regions. Kamada is headquartered in Rehovot, Israel.

For a complete picture of Alpha-1 proteinase inhibitor (human) second generation’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 7 February 2024

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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.