APSA-02 is a biologic commercialized by Armata Pharmaceuticals, with a leading Phase II program in Bacteremia. According to Globaldata, it is involved in 2 clinical trials, of which 1 is ongoing, and 1 is planned. GlobalData uses proprietary data and analytics to provide a complete picture of APSA-02’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for APSA-02 is expected to reach an annual total of $19 mn by 2038 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
APSA-02 is under development for the treatment of bacteremia, periprosthetic joint infections caused by staphylococcus aureus. It is administered by the intravenous route. The drug candidate is a bacteriophage and being developed based on proprietary synthetic phage platform. It is a biologic product candidate comprised of a cocktail of natural lytic phages that target the problematic pathogen, Staphylococcus aureus.
It was also under development for the treatment of pneumonia, endocarditis.
Armata Pharmaceuticals Overview
Armata Pharmaceuticals, formerly AmpliPhi Biosciences Corp, is a biotechnology company. It develops pathogen-specific bacteriophage drugs for the treatment of antibody-resistant bacterial infections. The company is investigating AP-PA02 drug against cystic fibrosis and non-CF bronchiectasis; and AP-PA03 to treat pneumonia. The company is also evaluating AP-SA02 program for the treatment of staphylococcus aureus infections such as bacteremia and periprosthetic joint infections (PJI). Armata Pharmaceuticals utilizes its proprietary synthetic phage platform to develop therapies for multidrug-resistant bacterial infections. It works in partnership with Merck & Co Inc to develop its products. Armata Pharmaceuticals is headquartered in Marina del Rey, California, the US.
The company reported revenues of (US Dollars) US$4.5 million for the fiscal year ended December 2021 (FY2021), compared to a revenue of US$0.8 million in FY2020. The operating loss of the company was US$23.1 million in FY2021, compared to an operating loss of US$22.7 million in FY2020. The net loss of the company was US$23.2 million in FY2021, compared to a net loss of US$22.2 million in FY2020. The company reported revenues of US$1.3 million for the third quarter ended September 2022, a decrease of 28.9% over the previous quarter.
For a complete picture of APSA-02’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.