ASC-42 is under clinical development by Ascletis Pharma and currently in Phase II for Primary Biliary Cholangitis (Primary Biliary Cirrhosis). According to GlobalData, Phase II drugs for Primary Biliary Cholangitis (Primary Biliary Cirrhosis) have a 42% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how ASC-42’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
ASC-42 overview
ASC-42 is under development for the treatment of non-alcoholic steatohepatitis (NASH), primary biliary cholangitis (primary biliary cirrhosis) and chronic hepatitis B. It acts by targeting farnesoid X receptor (FXR). It is administered orally as a tablet.
Ascletis Pharma overview
Ascletis Pharma is a pharmaceutical company that develops and commercializes novel drugs for unmet medical needs. The company operates as a investigating ASC09 inhibitor to treat HIV type-1 infections; and ASC06, a novel drug for the treatment of liver cancer through RNA interference. It is also advancing products against COVID-19 and fatty liver diseases. Ascletis Pharma utilizes anti-viral and RNAi platform to develop its pipeline products. The company works in partnership with Roche Holding AG; Presidio Networked Solutions LLC; Medivir AB; Janssen Pharmaceutical NV; and Alnylam Pharmaceuticals Inc for developing its products. Ascletis Pharma is headquartered in Hangzhou, Zhejiang, China.
For a complete picture of ASC-42’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.
