Aviptadil is under clinical development by Relief Therapeutics and currently in Phase II for Respiratory Tract Inflammatory Disorders. According to GlobalData, Phase II drugs for Respiratory Tract Inflammatory Disorders have a 33% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Aviptadil’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Aviptadil overview

Aviptadil is under development for the treatment of pulmonary sarcoidosis, coronavirus disease 2019 (COVID-19) pneumonia, checkpoint inhibitor-induced pneumonitis, chronic berylliosis, non-acute lung injury in coronavirus disease (COVID-19) and coronavirus disease (COVID-19) associated acute lung injury and coronavirus disease 2019 (COVID-19) associated acute respiratory distress syndrome. The drug candidate is administered through inhalation and intravenous route. Aviptadil is a synthetic analogue of 28 amino acid vasoactive intestinal polypeptide. It acts by targeting VIP receptors Vasoactive Intestinal Polypeptide Receptor 1 and Vasoactive Intestinal Polypeptide Receptor 2. It was also under development for the treatment of idiopathic pulmonary fibrosis, acute lung injury and pulmonary arterial hypertension.

Relief Therapeutics overview

Relief Therapeutics is a drug development company that offers clinical development of peptides and proteins of natural or engineered origin. Its pipeline drug candidates include PKU GOLIKE, ACER-001, APR-OD032, RLF-100, APR-TD011 and APR-TM011. The company offer its products in the therapeutic areas of rare metabolic disorders, rare pulmonary diseases, and rare connective tissue disorders, with particular emphasis on conditions with dermatological manifestations. It partners with academic institutions, healthcare researchers and patient support groups for product development and commercialization. Relief Therapeutics is headquartered in Geneve, Switzerland.

For a complete picture of Aviptadil’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 2 September 2023

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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.