AZD-0171 is under clinical development by AstraZeneca and currently in Phase II for Metastatic Pancreatic Cancer. According to GlobalData, Phase II drugs for Metastatic Pancreatic Cancer have a 31% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how AZD-0171’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
MSC-1 is under development for the treatment of metastatic pancreatic ductal adenocarcinoma (mPDAC), metastatic pancreatic cancer. The drug candidate is a humanized anti-LIF monoclonal antibody that is designed to target genes that are vital for cancer cells to grow and divide. These are developed based on phage display platform. The drug candidate is administered through intravenous route. It acts by targeting LIF (Leukemia Inhibitory Factor). It was also under development for glioblastoma multiforme, metastatic colorectal cancer, metastatic ovarian cancer, relapsed or refractory metastatic solid tumors, non-small cell lung cancer, head and neck cancer, melanoma, prostate cancer and metastatic pancreatic cancer
AstraZeneca is a biopharmaceutical company, which is focused on discovery, production and commercialization of a range of prescription drugs. It develops products related to therapy areas such as respiratory, cardiovascular, renal and metabolic diseases, cancer, autoimmune, infection and neurological diseases. The company’s product portfolio includes biologics, prescription pharmaceuticals and vaccines. AstraZeneca sells its products through wholly- owned local marketing companies, distributors and local representative offices. The company markets its products to primary care and specialty care physicians. The company operates in Europe, the Americas, Asia, Africa and Australasia. AstraZeneca is headquartered in Cambridge, Cambridgeshire, the UK.
For a complete picture of AZD-0171’s drug-specific PTSR and LoA scores, buy the report here.