BDC-3042 is under clinical development by Bolt Biotherapeutics and currently in Phase II for Melanoma. According to GlobalData, Phase II drugs for Melanoma have a 27% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how BDC-3042’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

BDC-3042 overview

BDC-3042 is under development for the treatment of KRAS and TP53 mutated solid tumors including bladder, PDAC, triple negative breast cancer, clear cell renal cell carcinoma, ovarian cancer, head and neck cancer, colorectal cancer, melanoma, endometrial cancer and non-small cell lung cancer. The drug candidate is administered through intravenous route and acts by targeting dectin-2.

Bolt Biotherapeutics overview

Bolt Biotherapeutics is a clinical-stage biopharmaceutical company that develops novel immunotherapies for the treatment of cancer. The company develops immuno-oncology therapeutics by using the Boltbody ISAC platform. Its pipeline products include BDC-1001 and BDC-3042. Its BDC-1001 product treats HER2-positive colorectal, endometrial, gastroesophageal and metastatic breast cancer. Bolt Biotherapeutics’ BDC-3042 product treats solid tumors. Its Boltbody ISAC platform works in collaboration with Genmab A/S, Innovent Biologics, Inc and Toray Membrane USA, Inc. Bolt Biotherapeutics is headquartered in Redwood City, California, the US.

For a complete picture of BDC-3042’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.