Beam Therapeutics. has been granted a patent for compositions and methods involving nanoparticles, including lipid nanoparticles, as well as nanomaterials. The patent includes a specific compound defined by Formula I. GlobalData’s report on Beam Therapeutics gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Beam Therapeutics, CRISPR genome editing was a key innovation area identified from patents. Beam Therapeutics's grant share as of July 2024 was 4%. Grant share is based on the ratio of number of grants to total number of patents.

Nanoparticles and methods for their use

Source: United States Patent and Trademark Office (USPTO). Credit: Beam Therapeutics Inc

The granted patent US12059477B2 outlines a series of claims related to novel compounds, specifically those represented by various chemical formulas, including Formula I and its derivatives. The claims detail the structural components of these compounds, such as specific substituents (R1, R1') and groups (A1, A2, —X2—X3), as well as various formulations (e.g., Formulas II, IIA, IIB, IIC, III, IIIA, IV, V, VA, VI, VIA). Additionally, the patent encompasses lipid nanoparticle (LNP) preparations that incorporate these ionizable lipids, which are essential for the delivery of therapeutic agents.

Furthermore, the patent describes multiple methods for utilizing the LNP preparations, including their administration for therapeutic and prophylactic purposes, treatment of diseases, and specific delivery to mammalian cells and organs. Notably, the methods also cover the production and inhibition of polypeptides of interest through the use of mRNA and RNA agents encapsulated within the LNPs. The claims extend to applications in vaccination and inducing adaptive immune responses, highlighting the potential of these compounds and formulations in therapeutic contexts.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies