BioGaia has been granted a patent for lactic acid bacterial strains capable of producing melatonin and adenosine for therapeutic use in treating diseases associated with melatonin deficiency, such as infantile colic. The patented strains include Lactobacillus reuteri DSM 32846, DSM 32847, DSM 32849, or DSM 33198. GlobalData’s report on BioGaia gives a 360-degree view of the company including its patenting strategy. Buy the report here.

Smarter leaders trust GlobalData


Data Insights BioGaia AB - Company Profile

Buy the Report

Data Insights

The gold standard of business intelligence.

Find out more

According to GlobalData’s company profile on BioGaia, Lactobacillus probiotics was a key innovation area identified from patents. BioGaia's grant share as of April 2024 was 48%. Grant share is based on the ratio of number of grants to total number of patents.

Melatonin-producing lactobacillus bacterial strains

Source: United States Patent and Trademark Office (USPTO). Credit: BioGaia AB

A recently granted patent (Publication Number: US11911424B2) discloses a bacterial strain, specifically Lactobacillus reuteri DSM 32846, DSM 32847, DSM 32849, or DSM 33198, with potential therapeutic applications. The patent claims cover the use of these bacterial strains in dried form, in combination products to increase the production of melatonin or adenosine in a subject, and in compositions aimed at inducing the production of melatonin or adenosine in a subject.

Moreover, the patent claims also extend to methods of treating conditions such as irritable bowel syndrome (IBS), sleep disorders, neurodegenerative diseases, and infantile colic by administering a therapeutically effective amount of the Lactobacillus reuteri strain. The methods outlined in the patent involve not only the administration of the bacterial strain but also the use of additional substrate components or agents to enhance the production of melatonin and/or adenosine in the subject. The patent highlights the potential of these methods to significantly increase the levels of melatonin and adenosine in the subject, thereby offering promising treatment options for various health conditions.

To know more about GlobalData’s detailed insights on BioGaia, buy the report here.

Data Insights


The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies