Birociclib is under clinical development by Sihuan Pharmaceutical Holdings Group and currently in Phase III for Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer). According to GlobalData, Phase III drugs for Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer) have a 52% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how Birociclib’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Birociclib overview

XZP-3287 (birociclib) is under development for the treatment of solid tumors including a malignant brain tumor and hormone receptor positive breast cancer, human epidermal growth factor receptor 2 negative breast cancer (HER2- breast cancer) and metastatic prostate cancer. It acts by targeting cyclin-dependent kinases (CDK) 4 and 6. It is administered orally as a tablet.

Sihuan Pharmaceutical Holdings Group overview

Sihuan Pharmaceutical Holdings Group (Sihuan Pharmaceutical) is a pharmaceutical company that develops, manufactures, and markets prescription drugs. It offers products in the therapeutic areas of cardio-cerebral vascular, digestive system, anti-infective, metabolism, respiratory, neurology and Others. Sihuan Pharmaceutical offers products under the brand names Tenedid, Tenaxin, Xiangtong, Aogan, Aohuan, Aoying, Aomeina, Ren’ao, Ashenqnuooqi, Aosaixin, and Huineng among others. The company sells its products through its distribution to network hospitals and medical institutions in Zhejiang, Guangdong, and Henan. Sihuan Pharmaceutical is headquartered in Beijing City, Beijing, China.

For a complete picture of Birociclib’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 15 September 2023

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.