Bomedemstat tosylate is under clinical development by Merck and currently in Phase III for Essential Thrombocythemia. According to GlobalData, Phase III drugs for Essential Thrombocythemia does not have sufficient historical data to build an indication benchmark PTSR for Phase III. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Bomedemstat tosylate LoA Report. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Bomedemstat tosylate overview
IMG-7289 is under development for the treatment of acute myelogenous leukemia (AML), polycythemia vera, essential thrombocythemia, myelofibrosis including post-polycythemia vera myelofibrosis (PPV-MF), post-essential thrombocythemia myelofibrosis (PET-MF), primary myelofibrosis and new chemical entities for hemoglobinopathies (hemoglobin deficiencies) and solid tumors (other malignances). It is administered through oral route. The drug candidate acts by targeting lysine specific demethylase 1 (LSD-1 or KDM1A).
It was under development for the treatment of myelodysplastic syndrome (MDS), small-cell lung cancer.
Merck overview
Merck is a biopharmaceutical company that focuses on the discovery, development, manufacturing and marketing of prescription medicines, biologic therapies, vaccines, and animal health products. It offers prescription products for the treatment of cardiovascular conditions, cancer, immune disorders, infectious and respiratory diseases, and diabetes, among others. The company provides animal health products such as vaccines, poultry products, livestock products and aquaculture products. Merck sells medicines to drug wholesalers, retailers, hospitals, government agencies and managed health care providers; and animal health products to veterinarians, distributors, and animal producers. The company and its subsidiaries operate in the Americas, Europe, the Middle East, Africa, Asia Pacific, and Latin America. Merck is headquartered in Rahway, New Jersey, the US.
For a complete picture of Bomedemstat tosylate’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
